Publications

COVID-19

Asger Givskov Jørgensen, Daniel Miotto Dupont, Søren Fjelstrup, Claus Bus, Cecilie Bo Hansen, Thomas Benfield, Peter Garred, Peter M.H. Heegaard, Jørgen Kjems. Unbiased plasma profiling using pre-selected RNA aptamer pools predicts mortality in COVID-19 and identifies protein risk factors.

Molecular Therapy – Nucleic Acids, Volume 35, Issue 3, 2024, DOI:
https://doi.org/10.1016/j.omtn.2024.102253

Bladder cancer

Fjelstrup S, Dupont DM, Bus C, Enghild JJ, Jensen JB, Birkenkamp-Demtröder K, Dyrskjøt L, Kjems J. Differential RNA aptamer affinity profiling on plasma as a potential diagnostic tool for bladder cancer.

NAR Cancer. 2022 Aug 22;4(3):zcac025. DOI:
https://doi.org/10.1093/narcan/zcac025

SELEX

Dupont DM, Larsen N, Jensen JK, Andreasen PA, Kjems J. Characterisation of aptamer-target interactions by branched selection and high-throughput sequencing of SELEX pools.

Nucleic Acids Res. 2015 Dec 2;43(21):e139. DOI:
https://doi.org/10.1093/nar/gkv700

MASLD

Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

Mikkel B. Kjær, Asger G. Jørgensen, Søren Fjelstrup, Daniel M. Dupont, Claus Bus, Peter L. Eriksen, Karen L. Thomsen, Jeyanthini Risikesan, Søren Nielsen, Charlotte W. Wernberg, Mette M. Lauridsen, Elisabetta Bugianesi, Chiara Rosso, Henning Grønbæk and Jørgen Kjems. Diagnosis and Staging of Metabolic Dysfunction-Associated Steatotic Liver Disease Using Biomarker-Directed Aptamer Panels.

Biomolecules 2025, 15(2), 255; https://doi.org/10.3390/biom15020255